Characterizing the Baseline Regional Biphasic Mechanical Properties of Cervical Intervertebral Discs.

ABSTRACT:

Purpose

While the regional viscoelastic biomechanical properties of lumbar intervertebral disc tissues are well documented, equivalent tissue-level characterizations for human cervical discs remain unexplored. This study aimed to quantify biphasic mechanical properties of the nucleus pulposus (NP), annulus fibrosus (AF), and cartilaginous endplate (CEP) in cervical discs.

Methods

A previously established confined compression testing technique was used to measure swelling pressure, equilibrium aggregate modulus, and hydraulic permeability in cervical NP, AF, and CEP tissues. Specimen-specific porosity was also assessed and correlated with these properties. A finite element model was used to simulate unconfined compression.

Results

Swelling pressure (154.50 ± 89.47 kPa)

SUBMITTER: Buchweitz N 

PROVIDER: S-EPMC12391200 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature