Effects of LIPOSA-T pharmacopuncture on localized fat as a fat dissolving injection via regulation of fat metabolism.

ABSTRACT:

Background

Excessive fat deposition in localized adiposity is known to induce severe medical diseases as well as aesthetic problems. Of late, LIPOSA-T pharmacopuncture, a new herbal pharmacopuncture consisting of the cortex of Morus alba and bark of Magnolia officinalis, is developed as a non-surgical injection for dissolving localized fat deposits.

Methods

The network pharmacology analysis was carried out with the target gene sets of constituents of M. alba and M. officinalis. Male C57BL/6 J mice were induced obesity and injected LIPOSA-T pharmacopuncture into inguinal fat pad. The fat weight and size were analyzed using dual energy X-ray absorptiometry.

Results

The possible pathways and mechanism of action of LIPOSA-T were found to be mai

SUBMITTER: Kim MH 

PROVIDER: S-EPMC12391440 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature