Crystalline Covalent Organic Framework Paper for Sweating Disorder Disease Analysis.

ABSTRACT: Abnormal sweating is closely associated with the occurrence and progression of various serious diseases, yet quantitatively and accurately assessing sweat pore function remains challenging. In this study, a crystalline covalent organic framework (COF) paper was developed for precise sweat pore analysis of sweating disorders. The delicately designed COF system achieved high-contrast sweat-responsive color change through the doping of sweat contents while showing no response to water, greatly enhancing resistance to environmental humidity interference. The flexible COF paper, grown in situ on PVDF paper substrates, adapts well to various skin surfaces, successfully recording the distribution and activity information on sweat pores through the "sweat pore mapping" technique of absorbing picol

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12391987 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature