Low Measles Seropositivity in Vaccinated Children.

ABSTRACT: India's goal of measles elimination remains unmet, as evidenced by significant recent outbreaks. To identify seroprevalence rates among vaccinated children and to examine demographic factors that influence antibody responses. This cross-sectional study included a highly vaccinated cohort of Indian children from the states of Kerala and Tamil Nadu between 2018 and 2023. Eligible children had received at least 2 doses of measles-containing vaccines; their mothers were recruited from various community settings, including local nursery and secondary schools, residential associations, and hospitals. Measles-specific antibodies were quantified in serum samples. Measles-specific immunoglobulin G (IgG) and neutralizing antibodies were quantified in both children and mothers. Measles-specific IgM w

SUBMITTER: Quach HQ 

PROVIDER: S-EPMC12391999 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature