Covalent Attachment of Molecularly Thin PVC Membrane by Click Chemistry for Ionophore-Based Ion Sensors.

ABSTRACT: Solid-contact ion-selective electrodes (SC-ISEs) are widely used in clinical diagnostics devices and are expanding into other fields including environmental and wearable sensors. Despite significant materials research efforts, the most widely used polymer for membrane preparation remains plasticized poly(vinyl chloride) (PVC). Owing to its nonreactive nature, it is normally applied onto the electrode substrate by evaporative solvent casting. Unfortunately, the resulting films tend to adhere poorly onto the electrode substrate and it is difficult to fabricate robust, well-defined sensing films with controlled thickness down to the nanoscale. This work introduces, for the first time, a PVC polymer membrane that is chemically bonded to the electrode substrate by Cu(I)-catalyzed azide-alkyne c

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12392254 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature