Effect of essential oils from <i>Cymbopogon citratus, Citrus grandis</i>, and <i>Mentha arvensis</i> on <i>Trichomonas vaginalis</i> and role of its symbionts <i>Mycoplasma hominis</i> and <i>Ca.</i> Mycoplasma girerdii.

ABSTRACT:

Introduction

Trichomoniasis, the most common non-viral sexually transmitted disease, is caused by the protozoon Trichomonas vaginalis. T. vaginalis can establish a symbiosis with two bacteria, Mycoplasma hominis and Candidatus Mycoplasma girerdii, whose intracellular presence may modulate several characteristics of the protozoan, including its sensitivity to 5-nitroimidazoles, the only class of drugs currently effective in treating trichomoniasis. The rising prevalence of T.vaginalis strains resistant to metronidazole, the most commonly used antitrichomonal drug, underscores the need for therapeutic alternatives active against the protozoon.

Methods

In this study, we evaluate the antimicrobial activity of essential oils extracted from three

SUBMITTER: Margarita V 

PROVIDER: S-EPMC12392280 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature