QCAV-4, the first genetically modified Cavendish (cv. Grand Nain) banana resistant to Fusarium wilt tropical race 4 approved for commercial production and consumption.

ABSTRACT: Bananas (Musa spp.) are a major fruit crop worldwide, with the Cavendish cultivar dominating the export industries, which are based primarily in the Americas and the Philippines. The sustainability of banana production in these, and other regions, is under threat from the fungal disease Fusarium wilt tropical race 4 (TR4) which kills Cavendish and many other banana cultivars. No effective TR4 control strategies exist, and no consumer-acceptable TR4-resistant Cavendish replacements are currently available. Previously, we identified four genetically modified (GM) TR4-resistant Cavendish (cv. Grand Nain) banana lines (RGA2-2, -3, -4, and -5), each transformed with the MamRGA2 resistance gene derived from a TR4-resistant wild banana. Here, we provide a comprehensive agronomic evaluation of the

SUBMITTER: Harding R 

PROVIDER: S-EPMC12392930 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature