A Granular Hydrogel-Enabled Wearable Electrochemical Biosensing Platform for Continuous Non-Invasive Sweat Lactate Detection.

ABSTRACT: Although continuous and non-invasive measurements of sweat biomarkers may provide vital health information, sweat collection often involves intense physical activities or chemical/thermal stimuli. The natural body sweat during endogenous metabolic or stress processes, secreted at much lower rates at rest, may be continuously analyzed using microfluidic devices integrated with hydrophilic rigid fillers; however, the sweat uptake and accumulation in thermoregulatory processes take too long for near-real-time measurements. This work provides an innovative body fluid collection strategy using a granular hydrogel scaffold (GHS), facilitating osmotic and capillary effects to uptake and transfer an ultralow amount of sweat into a microfluidic device at rest. Taken together with a spiral microflui

SUBMITTER: Lorestani F 

PROVIDER: S-EPMC12393019 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature