Cardiometabolic criteria as predictors and treatment targets of liver-related events and cardiovascular events in metabolic dysfunction-associated steatotic liver disease.

ABSTRACT:

Background

The diagnosis of metabolic dysfunction-associated steatotic liver disease (MASLD) requires at least one of five cardiometabolic criteria. It is unclear whether these criteria can be used as predictors and treatment targets for complications including liver-related events and major adverse cardiovascular events (MACE).

Aims

To investigate the relationship between cardiometabolic criteria and complications.

Methods

We conducted a nationwide, population-based study of 979,352 patients with MASLD. We investigated relationships between a number of criteria at baseline and liver-related events or MACE risks. In a separate longitudinal analysis, we included patients with five criteria at baseline and investigated the relationship between improving the criteria and

SUBMITTER: Tamaki N 

PROVIDER: S-EPMC12393157 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature