3D finite-element study for multi-frequency harmonic shear wave elastography: shear wave speed contrast assessment and experimental verification.

ABSTRACT: Towards the characterization of viscoelasticity of the soft tissue, which is an important biomarker, this study aims to investigate the effectiveness of the Harmonic Shear Wave Elastography (HSWE) framework by analyzing the frequency-dependent phase velocity maps, using a 3D Finite-Element-based simulation framework. Here, we developed and verified a 3D finite-element framework to accurately model the tissue displacement under a multi-frequency HSWE setting. The HSWE results were compared using both simulation and phantom experiments against those from the Pulsed Shear Wave Elastography (PSWE) method which is widely used in shear wave elastography problems. Particularly, we analyzed the group and frequency-dependent phase velocities, focusing on the frequency range of 300 to 800 Hz. Additi

SUBMITTER: Roy T 

PROVIDER: S-EPMC12393163 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature