Strong gradients, cool performance: A 64-channel array coil with concurrent field monitoring and thermal control for ex vivo diffusion-weighted brain imaging using the 3T connectome 2.0 MRI scanner.

ABSTRACT:

Purpose

High-resolution ex vivo diffusion-weighted imaging (dMRI) with high b$$ b $$ -values presents significant challenges, including low signal-to-noise ratio (SNR), magnetic field perturbations, and temperature-related measurement shifts. This work introduces a hardware-based solution to address these limitations in human ex vivo brain imaging.

Methods

A customized anatomically conformal 64-channel receive array coil with a dedicated Tx birdcage coil was developed for 3T diffusion-weighted imaging of whole human ex vivo brain specimens. Field monitoring capabilities were integrated to correct spatiotemporal field perturbations caused by gradient-induced eddy currents. Temperature stability throughout extended acquisition periods was achieved through an integrated stabili

SUBMITTER: Muller A 

PROVIDER: S-EPMC12393195 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature