Myelin water and tensor-valued diffusion imaging: (How) are they related?

ABSTRACT:

Purpose

Conventional MRI offers limited insight into specific characteristics of central nervous system tissue, whereas quantitative MRI measures can provide more detailed information about different aspects of microstructure. A multi-metric approach involving multiple quantitative measures may improve our understanding of healthy tissue and pathology. Previous work shows myelin water fraction (MWF) is related to fractional anisotropy (FA), but this relationship is complicated by confounding factors that may be resolved using tensor-valued diffusion imaging, which yields measurements of microscopic FA (μFA) and tissue heterogeneity (C_MD). Our aims were to better understand how measures from myelin water and tensor-valued diffusion imaging relate to one another, and to de

SUBMITTER: Balaji S 

PROVIDER: S-EPMC12393197 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature