Optimal dose and type of exercise improve the overall balance in adults with Parkinson's disease: a systematic review and Bayesian network meta-analysis.

ABSTRACT:

Objective

To investigate the dose-response relationship between various exercise modalities and their effectiveness in enhancing balance in Parkinson's disease (PD) patients.

Methods

Searches were conducted in PubMed, Medline, Embase, PsycINFO, Cochrane Library, and Web of Science from inception to July 23th, 2024. Data were analyzed using R software, with the MBNMA and RJAGS packages to compute standardized mean differences (SMD) and 95% credible intervals (95% CrI). The network's risk of bias was rigorously evaluated by two independent reviewers using the ROB2 tool.

Results

The analysis included 73 studies with 3,747 PD patients, assessing the effects of different exercises on balance. The findings demonstrate a nonlinear increasing dose-response relationship. Dance

SUBMITTER: Fan X 

PROVIDER: S-EPMC12394369 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature