Investigation of antibacterial and wound healing activities of the extract of Rhodotorula mucilaginosa endophyte isolated from cucumber leaves.

ABSTRACT: Endophytic fungi represent a reservoir of pharmacologically essential secondary metabolites. The current study focused on the antibacterial properties of the endophytic yeast-like fungus Rhodotorula mucilaginosa (R. mucilaginosa) isolated for the first time from Cucumis sativus (cucumber) leaves. After isolation, R. mucilaginosa was identified by 18S rRNA gene sequencing and was cultured on Asian rice for production of fungal metabolites. Then, its phytochemical profile was elucidated using LC-HRESI-MS/MS technique to reveal 22 compounds which are mainly carotenoids and fatty acids in nature. Dried ethyl acetate extract of R. mucilaginosa was tested for antimicrobial activity against Pseudomonas aeruginosa isolates. The extract of R. mucilaginosa (ERM) showed minimum inhibitory concentrati

SUBMITTER: Eliwa D 

PROVIDER: S-EPMC12394409 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature