Differential diagnosis between psoriatic arthritis and hand osteoarthritis using indocyanine green-based fluorescence optical imaging.

ABSTRACT:

Introduction

Fluorescence optical imaging (FOI) visualizes enhanced microcirculation in the hands as a marker for inflammation. The correct diagnosis of psoriatic arthritis (PsA) and erosive hand osteoarthritis (EHOA) can be challenging. The aim of this study was to differentiate active PsA from EHOA using FOI.

Methods

An atlas with FOI images of different grades of enhancement (FOIAS 0-3) and typical morphologic patterns ('Streaky signals', 'Green/Blue Nail sign', 'Werner sign', and 'Bishop's crozier sign') for PsA and hand EHOA was created. Twenty FOI sequences of patients with PsA and EHOA were randomly mixed and scored by two blinded readers. All images were scored twice by one of the two readers. Inter- and intra-reader reliability for joint enhancement, morphologic pat

SUBMITTER: Drude B 

PROVIDER: S-EPMC12394491 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature