Comprehensive pre- and in-hospital near-infrared-spectroscopy (NIRS) monitoring after return of spontaneous circulation predicts neurological outcome following out-of-hospital cardiac arrest: a prospective observational study and literature review.

ABSTRACT:

Background

An increase in regional cerebral oxygen saturation (rSO2) levels during advanced life support in patients with out-of-hospital cardiac arrest (OHCA) is associated with return of spontaneous circulation (ROSC) and can predict neurological outcome. Data from the post-ROSC phase are scarce but may predict clinical outcomes as well.

Methods

For this prospective observational study, we measured rSO2 via near-infrared spectroscopy (NIRS) in patients after ROSC following OHCA in both the pre- and in-hospital setting for up to 72 h. Patients were followed up for their post-ROSC treatment and outcomes. NIRS values were then compared between patients with favorable and non-favorable neurological outcomes, and cutoff values were assessed via receiver operating characteristic

SUBMITTER: Schnaubelt S 

PROVIDER: S-EPMC12394502 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature