Analysis of survival differences in advanced triple-negative breast cancer: a real-world study.

ABSTRACT:

Background

Advanced triple-negative breast cancer (aTNBC) has a poor prognosis, and there is a dearth of relevant real-world research data. This study is aimed at analyzing the survival outcomes and subgroup characteristics of aTNBC in the first-line treatment stage, providing data support for clinical treatment decisions.

Methods

A retrospective analysis was conducted on 215 patients with aTNBC who received first-line salvage treatment at Shandong Cancer Hospital from January 2018 to March 2023 (74 patients of de novo metastatic breast cancer [dnMBC] and 141 patients of recurrent metastatic breast cancer [rMBC]). Progression-free survival (PFS) and overall survival (OS) were assessed using the Kaplan-Meier method, and hazard ratio (HR) were calculated using the Cox r

SUBMITTER: Zheng JS 

PROVIDER: S-EPMC12394513 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature