Impact of vibrational strong coupling on liquid-liquid phase separation in supramolecular polymers.

ABSTRACT: Liquid-liquid phase separation (LLPS) is a universal phenomenon that plays a key role in many biological processes. Although LLPS is well known for (bio)macromolecular systems, we have recently demonstrated that supramolecular polymer systems can also undergo LLPS via an entropy-driven pathway. This opens new avenues for engineering biomaterials with tailored properties and functionalities by modulating the pathways of supramolecular polymerization. We have also shown that the energy landscape of supramolecular polymerization can be manipulated via light-matter strong coupling, without any chemical or real photon as input. Intrigued by these recent observations, we employed light-matter strong coupling to control LLPS driven by non-covalent high aspect ratio supramolecular po

SUBMITTER: Joseph K 

PROVIDER: S-EPMC12394911 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature