C-Reactive Protein as a Predictor of the Success of Debridement, Antibiotics and Implant Retention in Patients With Periprosthetic Joint Infection: A 17-year Retrospective Study of 2 Major Joint Arthroplasty Centers.

ABSTRACT:

Background

This retrospective study aims to investigate whether C-reactive protein (CRP) value following debridement, antibiotics, and implant retention (DAIR) procedure is a sensitive and specific marker to monitor the clinical course and predict the outcome of the DAIR procedure.

Methods

The electronic clinical management system was used to identify patients who suffered from the first episode of periprosthetic joint infection (PJI) following a total hip or knee arthroplasty and 2) and received DAIR as their first surgical treatment in 2 tertiary hospitals.

Results

Sixty-five patients were included in this study. Mean age was 68.5 and 55.7% were female. Mean follow-up duration was 3.31 years. 42 (64.6%) patients had successful DAIR while 23 (35.4%) had failed DAIR.

SUBMITTER: Kong CCW 

PROVIDER: S-EPMC12394966 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature