Neo-Sinus Washout Time Following Transcatheter Aortic Valve Replacement and Hemodynamic Outcomes.

ABSTRACT:

Background

Leaflet thrombosis and transcatheter heart valve dysfunction are key concerns following transcatheter aortic valve replacement (TAVR). Prolonged neo-sinus washout time (NWT) may predispose patients to hypoattenuated leaflet thickening (HALT) and leaflet thrombosis, increasing the risk of valve degeneration. This study evaluates the association between in vivo NWT derived from aortograms using computer vision and hemodynamic outcomes at 30 days and 1 year post-TAVR.

Methods

We retrospectively analyzed 2254 patients (mean age: 79 ​± ​9 years, 40% female) who underwent TAVR with balloon-expandable valves between 2016 and 2020. Patients were tertile stratified into tertile 1 (T1) (1.444-1.870 ​s; n ​= ​752), T2 (1.870-1.939 ​s; n ​= ​752), and T3 (1.939-2.110 ​s; n ​=

SUBMITTER: Ramu SK 

PROVIDER: S-EPMC12395173 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature