Efficacy and safety of electroacupuncture-based comprehensive treatment for post-stroke depression: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Objective

This research aims to assess the therapeutic effects and safety of treatments for PSD by conducting a thorough systematic review and meta-analysis.

Methods

Randomized controlled trials (RCTs) were retrieved from PubMed, Embase, Web of Science, The Cochrane Library, China National Knowledge Infrastructure (CNKI), and Wan Fang, covering all available records up to September 30, 2024. RCTs evaluating on the efficacy and safety of electroacupuncture in individuals with PSD were included. The robustness of the findings and possible contributors to heterogeneity were examined via sensitivity and subgroup analyses. Statistical analyses were conducted utilizing STATA 15.0 and Review Manager 5.4.

Results

This study included 65 RCTs with a total of 5,362 participants.

SUBMITTER: Hu X 

PROVIDER: S-EPMC12395381 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature