Premature ventricular contraction-induced ventricular dysfunction in children without structural heart disease: a systematic review and meta-analysis.

ABSTRACT:

Aims

Premature ventricular contractions (PVCs) in paediatric patients often present a benign course. However, a minority of patients may develop left ventricular (LV) dysfunction, and risk factors are still under debate. The aim of this systematic review and meta-analysis was to analyse the prevalence of PVC-induced cardiomyopathy (CMP) and understand the risk factors in paediatric patients with PVCs and structurally normal hearts.

Methods and results

A systematic search strategy was performed to identify original reports published between 1 January 2000 and 31 August 2024. Studies including adult patients and patients with cardiomyopathies, congenital heart diseases, or channelopathies were excluded. Seventeen studies were included and comprised 1.701 patients, with a mean

SUBMITTER: Flore F 

PROVIDER: S-EPMC12395427 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature