Formation and Reactivity of an Elusive Monomeric Mn(IV)-Oxo Species Inside a Cavitand Pore.

ABSTRACT: Metal-functionalized cavitands are promising platforms for mimicking the chemical environments of hydrophobic pockets in natural metalloenzymes. However, successfully combining the unique supramolecular capabilities of cavitand scaffolds with the high reactivities of transition metal complexes still remains a major challenge. In this study, we present an original cavitand architecture featuring a coordinatively unsaturated Mn(II) center embedded deep within its pore. This metallocavitand was employed to generate a Mn(IV)-oxo species inside a molecular cavity. This elusive intermediate was fully characterized spectroscopically (UV-vis, EPR, X-ray photoelectric spectroscopy (XPS), and HRMS) and, for the first time for a pseudo-octahedral Mn(IV)-oxo species, also by XRD. The experimental data

SUBMITTER: Green G 

PROVIDER: S-EPMC12395487 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature