Lymphocyte-to-Monocyte Ratio as a Predictor of Recompensation in Patients With Decompensated Primary Biliary Cholangitis.

ABSTRACT:

Background

Primary biliary cholangitis (PBC) patients in the decompensated stage face poor prognoses, with recompensation being crucial for improving long-term outcomes.

Aim

This study aims to evaluate the predictive value of the lymphocyte-to-monocyte ratio (LMR) for recompensation in decompensated PBC patients.

Methods

We retrospectively analysed 410 patients with PBC-related decompensated cirrhosis receiving ursodeoxycholic acid (UDCA) treatment. The association between the LMR and recompensation was examined using Cox regression analysis, with additional trend analysis performed based on LMR quartiles. The predictive accuracy of the LMR, neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII) and platelet-to-lymphocyte ratio (PLR) was evalua

SUBMITTER: Lin H 

PROVIDER: S-EPMC12395890 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature