The Impact of Acute Rheumatic Fever Diagnosis on Rheumatic Heart Disease Severity.

ABSTRACT:

Background

Acute rheumatic fever (ARF) is the precursor to rheumatic heart disease (RHD) following Group A Streptococcal infection. However, many diagnoses of RHD are made in the absence of ARF history. We compared RHD severity between those with and those without a documented history of ARF.

Methods

A retrospective audit of echocardiographic images determined RHD stage at diagnosis and at follow-up based on the 2023 WHF guidelines for the diagnosis of RHD.Individuals aged ≤ 20 years from the Top End of the Northern Territory (NT) of Australia with RHD diagnosis between January 2012 and December 2021 were included.Primary outcome was RHD stage at the time of diagnosis. Secondary outcomes were RHD stage progression or regression. Those with ARF and those with no ARF (noARF) w

SUBMITTER: Williamson JM 

PROVIDER: S-EPMC12396188 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature