Effect of Intravenous Lidocaine on Postoperative Cognitive Dysfunction in Patients Undergoing Laparoscopic Colorectal Surgery: A Two-Center, Randomized, Double-Blind Controlled Trial.

ABSTRACT:

Background

In patients undergoing gastrointestinal surgery, enhancing perioperative cognitive function and facilitating expedited postoperative recovery are critical components for achieving swift rehabilitation. Intravenous administration of lidocaine has been shown to mitigate the perioperative inflammatory response in surgical patients; however, its influence on postoperative cognitive performance remains unassessed. Consequently, this study was conducted to investigate the impact of intravenous lidocaine on postoperative cognitive function in participants undergoing laparoscopic surgery for colorectal cancer.

Methods

We performed a prospective, randomized controlled trial at The First People's Hospital of Changde City and Zhongshan People's Hospital to assess the impact

SUBMITTER: Liu KP 

PROVIDER: S-EPMC12396442 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature