Risk factors for dementia and cognitive impairment within 5 years after stroke: a prospective multicentre cohort study.

ABSTRACT:

Background

Stroke survivors frequently experience subsequent cognitive impairment or dementia. We aimed to identify risk factors for post-stroke dementia (PSD) and cognitive impairment (PSCI) within 5 years after stroke.

Methods

The DEMDAS (German Center for Neurological Diseases (DZNE) mechanisms of dementia after stroke) study is a prospective cohort of stroke patients admitted to six German tertiary stroke centres between May 1, 2011 and January 31, 2019. Eligible dementia-free patients with ischaemic or haemorrhagic stroke underwent baseline examinations and regular clinical, neuropsychological, and neuroimaging follow-ups over 5 years, with the last follow-ups completed in January 2024. PSD was the primary outcome, determined by comprehensive cognitive testing, patient

SUBMITTER: Filler J 

PROVIDER: S-EPMC12396445 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature