Emerging Riemerella anatipestifer infection in chickens: pathogenic characteristics and host immune response profiles.

ABSTRACT: The increasing Riemerella anatipestifer infection in chickens presents an emerging threat to the poultry industry. In the present study, we analyzed R. anatipestifer infection in chickens, including commercial layers, broiler breeders, broilers, and layer breeders, in 2024. The chicken-derived strain SD24-17-C was isolated from infected broilers and characterized. In vitro assays revealed the enhanced capabilities of SD24-17-C for adhesion and invasion to primary chick embryo fibroblasts; moreover, its reduced susceptibility to chicken serum was detected. These findings indicate enhanced infectivity of the strain in chickens. Based on the in vivo infection assay and associated clinical symptoms, mortality, organ indices, and histopathological features, we detected that the pathogenicity of

SUBMITTER: Lv J 

PROVIDER: S-EPMC12396462 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature