Evolving Changes in Centre-Level Utilization of Longer Distance Donors in Heart Transplantation.

ABSTRACT:

Objectives

This study evaluates changes in centre-level utilization of longer distance donors (LDD) in heart transplantation (HT) before and after the allocation policy change in 2018.

Methods

Adult HT recipients from 2010 to 2023 were identified from the United Network for Organ Sharing registry. Patients were categorized based on donor centre distance and policy change. The Mann-Kendall trend test was utilized for trend analysis. A propensity-matched analysis was performed. Survival analyses were performed using Kaplan-Meier, restricted mean survival time, and multivariable Cox proportional models. Interaction analysis with Bonferroni correction and sensitivity analysis to test the robustness of primary findings were performed.

Results

Among 32 036 recipients from 1

SUBMITTER: Bhandari K 

PROVIDER: S-EPMC12396783 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature