International, Multi-Institutional Evaluation of Practice Patterns and Outcomes for Recurrent and Metastatic Sinonasal Undifferentiated Carcinoma.

ABSTRACT:

Objectives

The aims of this study were to analyze the clinical characteristics of patients with recurrent and metastatic sinonasal undifferentiated carcinoma (SNUC) and evaluate the current treatment strategies to help guide future management.

Design

This is a retrospective cohort study.

Setting

The study was conducted at six international tertiary treatment centers.

Participants

Patients with documented diagnoses of recurrent or metastatic SNUC since 1983 were included in the study.

Main outcome measures

Patient demographics and clinical characteristics were collected. Primary outcome measures included disease-specific survival (DSS), overall survival (OS), and time to recurrence (TTR) following initial treatment. Further univariable and multivariable a

SUBMITTER: Saraswathula A 

PROVIDER: S-EPMC12396877 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature