Insights into pet-based radiogenomics in oncology: an updated systematic review.

ABSTRACT:

Purpose

This study systematically reviews current evidence on radiogenomics applied to positron emission tomography (PET) imaging across oncological diseases. The primary objective is to evaluate how PET-based radiogenomics aids in understanding tumor biology, prognostic stratification, and clinical outcome prediction, while identifying methodological challenges in the field.

Methods

A systematic review was conducted following PRISMA guidelines, focusing on English-language studies indexed in Scopus, PubMed, and Web of Science until October 31, 2024. Inclusion criteria targeted original research articles involving human oncology studies using radiomics and genomics in a comprehensive "omics" framework. Data extraction included patient cohorts, radiopharmaceuticals and statis

SUBMITTER: Filippi L 

PROVIDER: S-EPMC12396984 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature