Multi-parametric magnetic resonance imaging evaluation of a novel <i>ex ovo</i> chick chorioallantoic membrane model for cancer research.

ABSTRACT:

Background

The chick chorioallantoic membrane (CAM) tumor model has garnered significant interest due to its robust applications in research. However, there is a lack of understanding regarding the characteristics of nodules at different developmental stages and their corresponding imaging features. This study aimed to establish correlations between nodule attributes and magnetic resonance imaging (MRI) features via an ex ovo pancreatic cancer CAM model. Furthermore, this study explored the potential of functional MRI techniques in quantitatively discriminating pathological characteristics.

Methods

A total of 50 chicken embryos were cultured in ovo through embryonic day (ED) 3, then transferred to a customized chamber for ex ovo culture and subsequent ex

SUBMITTER: Feng G 

PROVIDER: S-EPMC12397616 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature