Quantitative analysis of macular and optic disc microvascular parameters in patients with immunoglobulin A nephropathy using optical coherence tomography angiography.

ABSTRACT:

Background

Immunoglobulin A nephropathy (IgAN) is a common chronic glomerulonephritis. The kidneys and eyes have structural and developmental similarities, but ocular microvascular changes in IgAN, especially in the macular and optic disc, are poorly studied. This study aimed to assess these microvascular parameters in IgAN patients using optical coherence tomography (OCT) and OCT angiography (OCTA) and explore their associations with clinical data.

Methods

This is a case-control study. Fifteen patients with IgAN and 15 healthy controls (HCs) who attended The Affiliated Hospital of Southwest Medical University between July 2022 and December 2023 were selected. OCT and OCTA were used to assess macular thickness, retinal nerve fiber layer (RNFL) thickness, the vascular density

SUBMITTER: Qiu C 

PROVIDER: S-EPMC12397639 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature