Evaluation of myocardial structure and function in hypertrophic obstructive cardiomyopathy via cardiovascular magnetic resonance: regional distribution and sex differences.

ABSTRACT:

Background

Although hypertrophy and fibrosis have been identified as contributors to mechanical dysfunction in patients with hypertrophic cardiomyopathy (HCM), their regional distribution and sex differences remain inadequately characterized in those with hypertrophic obstructive cardiomyopathy (HOCM). This study aimed to evaluate the determinants of myocardial strain deterioration across different regions and sexes of patients with HOCM through use of cardiovascular magnetic resonance feature tracking (CMR-FT) techniques.

Methods

This retrospective study included 102 patients with HOCM who underwent 3.0-T CMR. Global (G) and reginal left ventricular (LV) myocardial peak-strain parameters, including global longitudinal strain (GLS), global circumferential strain (GCS), and g

SUBMITTER: Bao Y 

PROVIDER: S-EPMC12397711 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature