Remote Screening for Asymptomatic Atrial Fibrillation: The AMALFI Randomized Clinical Trial.

ABSTRACT:

Importance

Screening for atrial fibrillation (AF) might reduce stroke if it increases long-term AF detection and anticoagulation use compared with usual care.

Objective

To investigate the long-term efficacy of AF screening in older individuals at moderate to high risk of stroke using 14-day, patch-based continuous ambulatory electrocardiogram (ECG) monitoring.

Design, setting, and participants

A parallel-group, unblinded, remote randomized clinical trial recruiting from 27 UK primary care practices from May 2, 2019, to February 28, 2022. All eligible individuals 65 years or older with a CHA2DS2VASc score of 3 or higher (men) or 4 or higher (women) with no previous AF or atrial flutter were identified via automated electronic health record searches. Last follow-up was

SUBMITTER: Wijesurendra R 

PROVIDER: S-EPMC12397955 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature