Systematic meta-review: diagnostic accuracy of colon capsule endoscopy for colonic neoplasia with umbrella meta-analysis.

ABSTRACT:

Background

Colorectal cancer (CRC) incidence is rising globally, intensifying pressure on endoscopy services. Colon capsule endoscopy (CCE) offers a non-invasive alternative. Despite several systematic reviews showing reasonable polyp detection rates, clinical scepticism remains.

Objectives

This meta-review and umbrella meta-analysis aim to synthesise evidence on CCE's diagnostic accuracy in polyp and CRC detection, using CT colonography or colonoscopy as the reference standard.

Methods

We conducted a systematic search of EMBASE, MEDLINE and PubMed for systematic reviews evaluating the diagnostic accuracy of CCE in detecting polyps and CRC. A qualitative thematic review and synthesis were conducted following PRISMA guidelines. A bivariate generalised linear mixed mode

SUBMITTER: Lei II 

PROVIDER: S-EPMC12398663 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature