Relationship between triglyceride-glucose index and all-cause mortality in older adults with sarcopenic obesity.

ABSTRACT:

Background

Sarcopenic obesity (SO) combines reduced muscle mass and increased fat, elevating health risks in older adults. The triglyceride-glucose (TyG) index, a marker of insulin resistance, is associated with metabolic dysfunction. However, its role in predicting mortality in SO remains unclear. This study investigates the TyG index as a potential predictor of all-cause mortality in older adults with SO.

Methods

This study examined SO trends using data from 30,137 adults with dual-energy X-ray absorptiometry (DXA) and body fat measurements (1999-2018). For mortality analysis, 706 participants from NHANES 1999-2004 were included. Sarcopenia was defined according to the 2014 FNIH criteria. Statistical analyses, including Cox regression, cubic splines, and subgroup analyses,

SUBMITTER: Huang Q 

PROVIDER: S-EPMC12398777 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature