Depth-to-scalp spatiotemporal dynamics for stereo-EEG.

ABSTRACT: The data obtained from stereo-elecroencephalography (SEEG) in patients with focal epilepsy are crucial for defining the epileptogenic zone and achieving successful resection, but suboptimal electrode placement impairs SEEG results. We demonstrate an approach for concurrent scalp and depth EEG analysis from one patient with successful intracranial workup and one in whom the seizure onset zone was unsampled by SEEG. Intracranial epileptiform discharges were identified and clustered, their scalp correlates were averaged, and electric source imaging (ESI) was applied to the resulting averaged scalp potential - depth-to-scalp ESI (dsESI). We found temporal differences between intracranial and scalp peaks, as well as variations in averaged scalp spikes morphology and propagation, expressed by th

SUBMITTER: Benoliel T 

PROVIDER: S-EPMC12399257 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature