The dietary inflammation index and body mass index mediate the association between the dietary index for gut microbiota and sarcopenia in older women: evidence from NHANES 2011-2018.

ABSTRACT:

Background

The dietary index of gut microbiota (DI-GM) was developed to assess dietary quality by reflecting the diversity of the gut microbiota composition. This study examined the relationship between DI-GM and sarcopenia risk and evaluated the potential moderating effects of diet-related factors on sarcopenia risk in adult individuals.

Methods

This cross-sectional study included 8,872 adults from the National Health and Nutrition Examination Survey (NHANES) database between 2011 and 2018. Weighted multivariable logistic regression, restricted cubic splines (RCS), and subgroup analyses were used to investigate the association between DI-GM and sarcopenia. Mediation analysis was employed to examine the impact of the dietary inflammatory index (DII), systemic immune-inflamma

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12399385 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature