Qiancao (<i>Rubia</i> spp.) - a comprehensive metabolomics analysis of the five core species.

ABSTRACT:

Introduction

Qiancao comprises five closely related species: Rubia cordifolia L., Rubia yunnanensis Diels., Rubia wallichiana Decne., Rubia schumanniana Pritz., and Rubia magna P. G. Xiao. Due to their similar morphological characteristics, alternative species are frequently substituted for R. cordifolia L. in traditional medicine. However, the latest National Pharmacopoeia of China only exclusively recognizes R. cordifolia L. as the official medicinal source. The metabolic differences among these species remain poorly characterized, largely owing to the absence of systematic metabolomic studies.

Methods

This study employed a metabolomics approach to investigate the five Rubia species. The selected species were analyzed

SUBMITTER: Zhang M 

PROVIDER: S-EPMC12399549 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature