Exploring Exercise-induced Long QT: A Scoping Review of Reversibility Through Detraining and Distinction from Long QT Syndrome.

ABSTRACT: Exercise-induced long QT may mimic congenital long QT syndrome (LQTS), risking misdiagnosis and unnecessary treatment. This scoping review explores its reversibility through detraining and differentiation from congenital LQTS. A systematic search of five databases identified six studies involving 196 subjects. Results showed that exercise-induced long QT is reversible, with QT intervals normalizing after detraining, typically over 1-6 months. Unlike congenital LQTS, affected athletes often lacked genetic mutations or family histories linked to the condition. The difference between congenital LQTS and exercise-induced long QT lies in the reversibility of QT interval prolongation. In those with exercise-induced long QT, the prolonged QT interval would return to normal levels with detraining,

SUBMITTER: Wiradinata W 

PROVIDER: S-EPMC12400174 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature