Lean body mass index and the risk of diabetes onset: A nationwide epidemiological cohort study.

ABSTRACT:

Aims/introduction

Diabetes causes microvascular complications and cardiovascular diseases, and identifying its risk factors is a critical issue. Muscle is a primary target organ of insulin; however, previous studies on the relationship between lean body mass and the risk of developing diabetes have reported inconsistent findings. This study aimed to evaluate the association between the predicted lean body mass index (LBMI), which can be easily calculated in daily clinical practice, and the risk of developing diabetes.

Materials and methods

This retrospective study analyzed a large scale real-world database to investigate the relationship between LBMI and diabetes risk in both men and women. The incidence of diabetes was determined using ICD-10 codes from an administrative cl

SUBMITTER: Aoyama K 

PROVIDER: S-EPMC12400360 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature