Micro- and Macrovascular Complications in Early-Onset Type 2 Diabetes in Indians: Prevalence and Predictors in a Prospective Cross-Sectional Study.

ABSTRACT:

Introduction

and Aims: The prevalence of T2DM is rising among young people, placing them at greater risk for complications. We studied the prevalence and predictors of micro- and macrovascular complications in early-onset diabetes subjects (EOD, <40 years) and compared with late-onset T2DM (LOD, ≥40 years).

Methods

A total of 800 subjects (400 EOD, 400 LOD), matched for gender and diabetes duration, were prospectively recruited and assessed for the prevalence of peripheral neuropathy, retinopathy, nephropathy, and ASCVD. Multivariate logistic regression analyzed predictors of diabetes complications.

Results

The median age at diagnosis of diabetes was 35 years in EOD and 48 years in LOD. Hypertension was more common in LOD (73.8% vs. 58.8%, p<0.001). EOD patients had h

SUBMITTER: Singhal A 

PROVIDER: S-EPMC12400502 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature