Transcriptome and metabolome reveal the accumulation of secondary metabolites in different species of Dioscorea.

ABSTRACT:

Background

The genus Dioscorea is traditional Chinese medicine producing a variety of pharmacological active substances especially saponins. In our study, the secondary metabolism of Dioscorea zingiberensis and D. opposita that have significantly different saponin contents were investigated.

Result

The saponin content was significantly different between two species. KEGG pathway enrichment analysis of transcriptomic data revealed significant differences between the two species in several metabolic pathways, including secondary metabolite biosynthesis, phenylpropanoid biosynthesis, starch and sucrose metabolism, photosynthesis, flavonoid biosynthesis, and steroid biosynthesis. Notably, 28 differentially expressed genes (DEGs) were linked to steroid biosynthesis. Through furth

SUBMITTER: Li WY 

PROVIDER: S-EPMC12400552 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature