Comprehensive preventive treatments for episodic migraine: a systematic review of randomized clinical trials.

ABSTRACT:

Background

Episodic migraine is a prevalent and disabling neurological disorder with a significant impact on quality of life and productivity. Preventive treatment aims to reduce the frequency, intensity, and disability associated with migraine attacks. However, the comparative efficacy and safety of available preventive strategies remain insufficiently addressed in the literature, especially in low- and middle-income countries.

Objective

To evaluate the efficacy and safety of pharmacological and non-pharmacological preventive treatments for episodic migraine through a systematic review and meta-analysis of randomized controlled trials (RCTs).

Methods

Following PRISMA guidelines, a comprehensive literature search was conducted across Wiley Online, BVS, MEDLINE, and OV

SUBMITTER: Velez-Jimenez MK 

PROVIDER: S-EPMC12400932 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature