High hydrostatic pressure enhanced the growth of deep-sea <i>Thermococcus aciditolerans</i> by promoting the reduction of elemental sulfur.

ABSTRACT: Thermococcus species are ubiquitously distributed across both shallow and deep-sea hydrothermal vent ecosystems. Elemental sulfur (S°) reduction plays a pivotal role in their energy metabolism. While extensive characterization of the MBS and MBH pathways, along with their SurR-dependent regulatory network, has been established in shallow-water model strains, understanding of the high hydrostatic pressure (HHP) and sulfur-responsive regulation of these pathways in deep-sea Thermococcus lineages remains limited. In this study, we investigated the effects of HHP on both growth and S° reduction in the deep-sea SY113 strain, as well as its regulatory impact on mbs and mbh expression. Our results demonstrate that HHP enhances both S° reduction and growth in SY113 stra

SUBMITTER: Jiao ZX 

PROVIDER: S-EPMC12401011 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature