Diagnostic value of Ep300 and FOXO4 proteins in acute ischemic stroke: preliminary findings from a case-control study.

ABSTRACT:

Background

Stroke is a leading cause of death and disability worldwide, and there is still a lack of specific and sensitive biomarkers for its diagnosis.

Objective

This study aimed to investigate the diagnostic value of FOXO4 and Ep300 proteins in acute ischemic stroke patients who visited the emergency department.

Methods

Patients were consecutively included in the study. The amount of Ep300 and FOXO4 proteins was determined using an enzyme-linked immunosorbent assay (ELISA). Receiver operator characteristic (ROC) analyses of FOXO4 and Ep300 proteins were performed.

Results

The study was conducted on a total of 39 acute ischemic stroke patients, 17 females and 22 males, with a mean age of 66.9 ± 11 years. Seventeen females and 23 male control were also include

SUBMITTER: Bulbul E 

PROVIDER: S-EPMC12401024 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature