Universal cervical-length screening to prevent preterm birth in twin pregnancy: cost-utility analysis.

ABSTRACT:

Objective

The purpose of this cost-utility analysis was to model the clinical and economic impact of three cervical-length screening strategies among low-risk twin pregnancies: two-step universal screening (at 18-20 and 20-22 weeks), one-step universal screening (at 18-20 weeks) and no screening.

Methods

This study used a decision-analytic model (decision tree and cohort state transition model) with a 100-year time horizon in a Canadian context. The population included dichorionic diamniotic twin pregnancies without a history of preterm birth or prophylactic progesterone or cerclage. The model assumed that vaginal progesterone was initiated for cervical length ≤ 25 mm and that cervical cerclage was performed plus vaginal progesterone treatment for cervical length ≤ 15mm. The

SUBMITTER: Khaikin Y 

PROVIDER: S-EPMC12401501 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature