Primary renal diffuse large B-cell lymphoma presenting as new-onset kidney failure.

ABSTRACT:

Background

Primary renal lymphoma is a rare form of kidney tumor, accounting for less than 1% of all kidney masses, and with only a few pediatric cases reported in the literature. Bilateral forms can present with kidney failure, constituting a therapeutic challenge for both hematologists and nephrologists, with the need to combine complex chemotherapy regimens and kidney replacement therapy.

Methods

We present a rare case of primary bilateral renal diffuse large B-cell lymphoma in a teenage girl presenting with kidney failure (eGFR of 7 ml/min/1.73 m²), proposing a practical approach to optimize chemotherapy on kidney replacement therapy. We discuss diagnostic methods, the management and adjustment of chemotherapy and hyperhydration protocols, and the tailoring of

SUBMITTER: Bertacchi M 

PROVIDER: S-EPMC12401750 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature