A validated LC-MS/MS multi-method for the determination of 110 mycotoxins and plant toxins in cow milk and application to samples from Germany.

ABSTRACT: Milk is widely consumed across all ages and is essential for dairy production. Milk quality and safety are largely influenced by the animal's diet, which may contain feedborne contaminants. This can lead to multi-toxin exposure, potentially transferring toxins to milk and posing health risks to consumers. Currently, only aflatoxin M1 (AFM1) is regulated by the European Union in milk (maximum level (ML) = 0.05 µg/kg) but the (co-)occurrence of other toxins should also be investigated. In this work, a QuEChERS-based LC-MS/MS multi-method for the simultaneous determination of 72 mycotoxins and 38 plant toxins in raw cow milk was developed and validated according to the latest EU regulations. The method showed excellent recoveries (87% of the analytes have average recoveries within 70-120%) an

SUBMITTER: El-Khatib AH 

PROVIDER: S-EPMC12401758 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature